Mario Notaristefano studied with Michele Marasco and then with Andrea Oliva at the Accademia Nazionale di Santa Cecilia in Rome. An important milestone in his artistic development was his encounter with Mario Caroli, who had a profound musical influence on him and with whom he studied at the Conservatorio della Svizzera Italiana (Swiss), as well as at the Musikhochschule Freiburg (Germany).
During his studies he attended masterclasses with renowned flutists such as Patrick Gallois, Barthold Kuijken, Davide Formisano, Annamaria Morini.
He is laureat of several major music competitions, among which are Cimarosa International Flute Competition, 7° International Competition Giovani Musicisti Treviso, Krakamp. Member of the Ensemble Aventure, he has performed with numerous orchestras including SWR Südwestrundfunks Symphonieorchester, Frankfurt Opern, Philharmonisches Orchester Freiburg, Basel Sinfonietta, Basel Symphonieorchester, Neue Philarmonie Westfalen, Strasbourg Philharmonique, Philharmonisches Orchester Würzburg, Teatro Petruzzelli di Bari, Teatro Comunale di Modena.
As a part of his constant endeavor to deepen his musical research and interpretation, Mario published the essay Luciano Berio tra poetiche del caso e postavanguardia, Studi di Estetica (Clueb, 44, 2012) for the University Alma Mater Studiorium of Bologna and Luciano Berio – Sequenza I , De Musica (17, 2013) for the University of Milan . Since 2018 Mario is teaching flute at the Hochschule für Musik in Freiburg (Germany).